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KMID : 0371619920080010001
Journal of Wonkwang Medical Science
1992 Volume.8 No. 1 p.1 ~ p.6
Changes in Urinary Excretion of Renal Tubular Enzymes after Extracorporeal Shock Wave Lithotripsy



Abstract
Urinary enzyme testing has been used by many investigators to diagnose and monitor various types of renal injury caused by extracorporeal shock wave lithotripsy. Two urinary enzymes, N-acetyl-beta-glucosaminidase(NAG), B2-microglobulin, were
monitored
in 22 patients 1 day before and 1 and 3 days after a single unilateral extracorporeal shock wave lithotripsy for treatment of renal stone. All patients had non-obstructed and infection-free previously untreated renal stones. Extracorporeal shock
wave
lithotripsy was performed on the EDAP-LTO1+pieoerectric lithotriptor. Urine specimens were collected before extracorporeal shock wave lithotripsy. 1 and 3 days after treatment. Two enzyme levels were elevated 1 day after treatment and decreased
to
pre-procedure levels at 3 days after, with the increases being statistically non-significant. These findings indicate that there is a transient, nonsignificant renal tubular damage after extracorporeal shock wave lithotripsy.
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